The call is coming from inside the house! It’s your mother, and she’s disappointed in your life decisions.
After a long and tortuous battle, the villain is vanquished. You go to bed, thinking you’re safe at last. Suddenly, from out of nowhere, regrets about your last relationship hit you.
The perpetrator was the twin you never knew you had. They’re happily married, own a nice house and keep asking when you’ll settle down.
The hillbilly family that you thought were harmless eccentrics turned out to be cannibals. Also, despite how much you mock and shun their simple lifestyle, they are clearly much happier than you.
The imaginary monster you feared as a child becomes real and hunts you down as an adult. It’s massively underwhelming compared to your current fears.
The dead rise from the grave to inform you that you’re squandering the wealth and resources they left you.
After an unspecified apocalypse reduces humanity to scattered groups of desperate survivors clinging together both for survival and to fulfill the simple emotional need of human contact, you discover that people still don’t want to hang out with you.